SLU Global Bioinformatics Centre

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Genomic comparison of Escherichia coli serotype O103: H2 isolates with and without verotoxin genes: implications for risk assessment of strains commonly found in ruminant reservoirs



Authors: **Söderlund, R.**, **Hurel, J.**, Jinnerot, T., Sekse, C., Aspán, A., Eriksson, E., & **Bongcam-Rudlof

Date: 2016

Abstract:

Escherichia coli O103:H2 occurs as verotoxigenic E. coli (VTEC) carrying only vtx 1 or vtx 2 or both variants, but also as vtx-negative atypical enteropathogenic E. coli (aEPEC). The majority of E. coli O103:H2 identified from cases of human disease are caused by the VTEC form. If aEPEC strains frequently acquire verotoxin genes and become VTEC, they must be considered a significant public health concern. In this study, we have characterized and compared aEPEC and VTEC isolates of E. coli O103:H2 from Swedish cattle.